Caffeine
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Food & Feed Additive
58-08-2
| CAS No. | 58-08-2 |
|
Appearance |
white,crystals |
20kg carton
25kg bag
| Characters | White or almost white,crystalline powder or silky white or almostwhite,crystals | |
| Solubility | Sparing soluble in water,freely soluble in boiling water,slightly soluble in ethanol (96%).It dissolves in concentrated solutions of alkali benzoates or salicylates.It sublimes readily. | |
| Identifications |
IR-The sample spectrum complies with that of the reference standard spectrum
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| Appearance of solution | Solution S is clear and colourless | |
| Melting point | 235.0℃~237.5℃ | |
| Other alkaloids | Compliance | |
| Acidity | Not more than 0.2 mL of 0,01 M sodium hydroxide is required to change t he colour of the indicator to blue |
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| Easy carbonization | Compliance | |
| Loss on drying | ≤0.5% | |
| Residue on ignition | ≤0.1% | |
| Sulfate | ≤500ppm | |
| Heavy metals (as Pb) | ≤10ppm | |
| Lead | ≤1ppr | |
| Arsenic | ≤2.0ppm | |
| Mercury | ≤2.0ppm | |
| Related substances | Any other impurity ≤0.5times the area of solution(a)(0.10%)
Total impurities ≤0.5times the area of solution(a)(0.10%) |
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Caffeine has high stability in acid and heated conditions.
Caffeine is a stimulant of the central nervous system. Caffeine can replace adenosine to bind to nerve cells, and thereby preventing adenosine from affecting the operation of the nervous system to keep the brain excited
Each gram of caffeine is soluble in 46 ml of water, 5.5 ml of hot water (80℃), 1.5 ml of boiling water, 66 ml of ethanol, 22 ml of hot ethanol (60℃), 50 ml of acetone, 5.5 ml of chloroform, 530 ml of ether, 100 ml of benzene, or 22 ml of boiling benzene. Caffeine is highly soluble in pyrrole and tetrahydrofuran containing 4% water, and it is soluble in ethyl acetate, slightly soluble in petroleum ether.
